Author : AIDEVI
Nicotinamide mononucleotide (NMN) has been getting a lot of buzz in recent years as researchers and aging and longevity experts like Harvard University professor David Sinclair have dug into its potential to help you live longer.
So Amazon’s recent decision to stop selling NMN comes as something as a buzzkill. A letter from Amazon’s Restricted Products Team told sellers that NMN products would be banned after March 13, 2023.
The move isn’t a total surprise: In November, 2022, the FDA decided to ban NMN as a supplement and sent published letters to NMN suppliers saying that NMN can no longer be sold in the U.S. as a supplement.
The reason: NMN, a NAD+ precursor, “has been authorized for investigation as a new drug.” That makes some sense, given the potential benefits researchers have sussed out so far.
NMN and Safety, According to Science
Nicotinamide mononucleotide (NMN) is a molecule that is naturally produced by the body and is involved in various biological processes. NMN has gained popularity as a dietary supplement due to its potential anti-aging and health-promoting effects. However, concerns have been raised about the safety of NMN supplementation. In this article, we will examine what the available scientific research says about the safety of NMN.
Scientific Research on the Safety of NMN
Numerous scientific studies have been conducted to examine the safety of NMN. While some animal studies have suggested that high doses of NMN may cause liver or kidney damage, studies in humans have not found any evidence of these adverse effects. In fact, a recent study published in the journal Nature Communications found that NMN supplementation was well-tolerated in healthy adults and did not cause any adverse effects on kidney function. Another study published in the journal Cell Reports found that NMN supplementation improved glucose tolerance in mice, without causing hypoglycemia in healthy human volunteers.
Leading Authorities on the Safety of NMN
In addition to the scientific research, leading authorities in the field of longevity science have also weighed in on the safety of NMN. Dr. David Sinclair, a Harvard professor and one of the world's leading experts on aging, has been a vocal proponent of NMN and its potential health benefits. In his book "Lifespan: Why We Age and Why We Don't Have To," Sinclair discusses the safety of NMN, stating that "there is no evidence of toxicity or side effects from NMN in any of the animal or human studies to date."
Similarly, Dr. Rhonda Patrick, a biomedical scientist and expert in aging and nutrition, has also spoken about the safety of NMN. In an interview with Joe Rogan, Patrick discussed the potential benefits of NMN and its safety, stating that "there's been a lot of research looking at the safety profile of NMN and there's really no indication that it's unsafe at this point."
Conclusion
Overall, the scientific research to date and leading authorities in the field of longevity science have all drawn the same conclusion — there is no evidence of any untoward side effects in reasonable doses of NMN. While concerns have been raised about the potential for NMN to cause liver or kidney damage or hypoglycemia, studies in humans have not found any evidence of these adverse effects. As with any new supplement, it's always a good idea to consult with a healthcare professional before taking NMN, but the available evidence suggests that NMN is a safe dietary supplement when taken at recommended doses, which means you can take your daily Wonderfeel NMN without worry. Wonderful news, isn’t it?